PAPPA, pappalysin 1, 5069

N. diseases: 125; N. variants: 12
Disease: Carcinoma, Ovarian Epithelial ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		0.030 Biomarker disease BEFREE This study further tests the efficacy of PAPP-A inhibition with a monoclonal antibody inhibitor (mAb-PA) in ovarian cancer (OC) platinum-resistant patient-derived xenograft (PDX) models. 31751381 2019
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		0.030 Biomarker disease BEFREE Together, these data indicate PAPP-A as a potential palliative and adjunct therapeutic target for women with ovarian cancer. 25695953 2015
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial 		0.030 Biomarker disease BEFREE To investigate the effect of PAPP-A in humans, we compared serum and ascites from 22 women with ovarian carcinoma. 26336825 2015