PAX4, paired box 4, 5078

N. diseases: 63; N. variants: 8
Disease: Hyperglycemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.130 GeneticVariation disease BEFREE Mutations in the PAX4 gene may be associated with impaired differentiation/development of pancreatic islet beta cells during fetal development and, consequently, a compromised insulin response to high blood glucose. 28730907 2018
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.130 Biomarker disease BEFREE Finally, direct administration of Ad5.Pax4 into the pancreas of insulin-deficient mice ameliorated hyperglycemia. 26435408 2016
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.130 AlteredExpression disease BEFREE Pax4 expression was increased in islets derived from Type 2 diabetic donors correlating with hyperglycaemia. 17989064 2008
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.130 Biomarker disease HPO