PBX3, PBX homeobox 3, 5090

N. diseases: 60; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.040 AlteredExpression disease BEFREE We found that PBX3 expression levels positively correlated with glioma mesenchymal markers. 30016974 2018
CUI: C0017638
Disease: Glioma
Glioma
0.040 AlteredExpression disease BEFREE Twenty-four human glioma and paired adjacent nontumorous tissues were collected for determination of miR-320 and PBX3 expression using RT-qPCR and western blot assays. 28934982 2017
CUI: C0017638
Disease: Glioma
Glioma
0.040 Biomarker disease BEFREE Silencing of PBX3 using small interfering RNA inhibited the migratory and invasive capacities of glioma cells, whereas reintroduction of PBX3 into glioma cells reversed the anti-invasive function of miR-98. 28124208 2017
CUI: C0017638
Disease: Glioma
Glioma
0.040 Biomarker disease BEFREE The results showed that PBX3 knockdown inhibited glioma cell proliferation and induced apoptosis, while PBX3 overexpression significantly promoted glioma cell proliferation. 28856521 2017