DisGeNET - a database of gene-disease associations

PBX3, PBX homeobox 3, 5090

N. diseases: 60; N. variants: 10

Disease: Malignant neoplasm of stomach ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

Biomarker

disease

BEFREE

MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation.

31662823

2019

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

Biomarker

disease

BEFREE

The present study underlines the significance of HOXA9/PBX3 in the development of gastric cancer.

29113222

2017

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

AlteredExpression

disease

BEFREE

PBX3 was overexpressed in GC tissues and promoted EMT in GC cells.

28111340

2017