SERPINA5, serpin family A member 5, 5104

N. diseases: 185; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE We sought to examine the impact of AKI and its predictors in diabetic patients with multivessel coronary artery disease undergoing PCI vs. CABG. 31230933 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 AlteredExpression disease BEFREE For 401 patients with stable CAD who were indicated for PCI, baseline hs-cTnI levels were measured before PCI for two times (the average: pre-PCI hs-cTnI) and 10 months after PCI (post-PCI remote hs-cTnI). 30600349 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE Twelve (86%) patients underwent PCI for stable coronary artery disease and 2 (14%) had unstable angina. 31175527 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE They dwell on the 'either/or' decision for selected patients suitable for both treatments, but provide little guidance for the majority of 'real world' patients with comorbidities precluding CABG, or complex coronary heart disease precluding PCI. 30846525 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The most common causes for the presence of unrevascularized CAD included the presence of chronic total occlusion in the native/graft vessels (49.7%) and diffuse/complex CAD unsuitable for PCI (24.6%). 31267799 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE As confirmed by our results, FFR and CFR are complementary; they could jointly contribute to better PCI guidance through the CFR-to-FFR ratio in patients with coronary artery disease. 30616240 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE We sought to compare long-term outcomes of MV PCI and CABG in patients with severe coronary artery disease (CAD) presenting with NSTE-ACS. 30251246 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The major indication for PCI was stable CAD, whereas acute coronary syndrome represented 30% of the patients. 31730255 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE Bivariate analysis revealed comparatively reduced statin use among patients without other cardiovascular risk factors including hypertension (63% vs. 39.3%; P < 0.0001) and coronary artery disease (CAD) with or without prior cardiac revascularization (coronary artery bypass grafting [CABG]/percutaneous coronary intervention [PCI]; 75.2% vs. 47.4%; P < 0.0001). 28602895 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE We studied 1316 patients with CAD and preserved renal function (estimated glomerular filtration rate ≥60 mL/min/1.73 m<sup>2</sup>) who underwent their first PCI between 2000 and 2011 and had data available for pre-procedural serum albumin. 29289574 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE <b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed. 29867494 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE We consecutively enrolled: a) 40 patients undergoing PCI of a chronic coronary total occlusion (CTO); b) 26 patients with ST-elevation myocardial infarction (STEMI) undergoing primary PCI (pPCI) of the infarct-related artery (IRA); c) 12 control patients undergoing angiography without significant coronary artery disease (CTRL). 29602581 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE Patients after myocardial infarction, stroke or therapeutic interventions [such as PCI for coronary artery disease (CAD)] with lower TH levels appear to have increased morbidity and mortality. 30069456 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The results indicate that a person-centered approach is useful in explaining heterogeneity in recovery from PCI, and may enhance personalized medicine in patients with CAD. 29704656 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The LRP Study is an international, multicenter, prospective cohort study conducted in patients with suspected coronary artery disease (CAD) who underwent cardiac catheterization with possible ad hoc PCI for an index event. 28938968 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE Potent anti-hypertension may influence the occurrence time of AEs after PCI in patients with coronary heart disease complicated hypertension. 28745786 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The GuideLiner-Sleeve Technique: A Novel Technique for High-Risk PCI Using Two Left Main Guides for Orbital Atherectomy of Two-Vessel Calcified Ostial Coronary Artery Disease. 29086733 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE We enrolled patients with coronary artery disease who underwent PCI with stenting. 28915645 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE Data of consecutive patients with NSTEMI and MVCAD treated in high-volume PCI center between 2006 and 2012 and included in the prospective registry were divided according to the presence of CTO and analyzed. 27888750 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The strongest predictors of use of ECMO, TH, coronary angiogram, and PCI were younger age and the presence of coronary artery disease. 28494635 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE A literature review was performed for trials studying revascularization, via CABG or PCI, in patients with CAD and LV dysfunction. 28707392 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE PCI Choice: Cardiovascular clinicians' perceptions of shared decision making in stable coronary artery disease. 28110953 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE The role of coronary revascularisation with PCI and CABG in patients with stable and unstable coronary artery disease (CAD) is well established and there is a general consensus among guidelines as regards the indications for coronary revascularisation. 28844035 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE In a planned sub-analysis of the Rosuvastatin For REduction Of Myocardial DamagE During Coronary AngioplastY (REMEDY) trial, 38 patients with stable CAD on chronic low-dose statin therapy were randomized, in a double-blind, placebo-controlled design, into 4 groups before PCI: i. placebo (n = 11); ii. atorvastatin (80 mg+40 mg, n = 9); iii. rosuvastatin (40 mg twice, n = 9); and iv. rosuvastatin (5 mg) and ezetimibe (10 mg) twice, (n = 9). 28394933 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE A multicenter collaborative analysis was performed on all consecutive patients with native coronary artery disease undergoing PCI with intravascular imaging-guided BVS implantation. 27865187 2017