ANGPTL4, angiopoietin like 4, 51129

N. diseases: 198; N. variants: 8
Disease: Tumor Angiogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 Biomarker phenotype BEFREE These showed that ANGPTL4 is a genetically and epigenetically inactivated secreted tumor suppressor that inhibits tumor angiogenesis. 23686315 2014
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 AlteredExpression phenotype BEFREE In summary, we demonstrated that EGFRvIII induces Angptl4 expression through the ERK/c-Myc pathway and promotes tumor angiogenesis in malignant gliomas. 23617883 2013
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 GeneticVariation phenotype BEFREE In vivo, the combination of Ad-HARPΔ111-136 and radiation therapy resulted in a striking inhibition (92%) of the growth of U87MG xenografts, resulting from the potent effect on tumor angiogenesis and tumor cell apoptosis as determined by TUNEL analysis. 21109939 2011