DCTN4, dynactin subunit 4, 51164

N. diseases: 253; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.030 Biomarker disease BEFREE XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation. 30275562 2019
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.030 Biomarker disease BEFREE Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent increase of the autophagy markers LC3B, p62 and autophagic vesciles upon increasing concentrations of the autophagy inhibitor chloroquine, which was demonstrated by immunoblotting, immunofluorescence and electron microscopy. 28903368 2017
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.030 AlteredExpression disease BEFREE Of 64 colon cancer tissue specimens examined, 48 tissues (75.0%, 48/64) expressed p62, while normal colon tissues did not show any expression of p62 (0/34). 23421499 2013