CYB5R4, cytochrome b5 reductase 4, 51167

N. diseases: 7; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.300 GeneticVariation disease UNIPROT
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 GeneticVariation disease BEFREE Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus. 15504981 2004
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 Biomarker disease MGD Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. 15247412 2004
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE Thus, variation in the coding region of NCB5OR is not a major contributor in the pathogenesis of nonautoimmune diabetes. 15504981 2004
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. 15247412 2004
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 Biomarker group BEFREE Thus, variation in the coding region of NCB5OR is not a major contributor in the pathogenesis of nonautoimmune diabetes. 15504981 2004
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.020 Biomarker group BEFREE Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. 15247412 2004
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		0.010 GeneticVariation phenotype BEFREE Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus. 15504981 2004
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		0.010 AlteredExpression phenotype BEFREE At 4 weeks of age, Ncb5or-/- mice have normal blood glucose levels but impaired glucose tolerance. 15247412 2004
CUI: C0342276
Disease: Maturity onset diabetes mellitus in young
Maturity onset diabetes mellitus in young 		0.010 Biomarker disease BEFREE We therefore considered NCB5OR to be a biological and positional candidate gene and examined the coding region of NCB5OR in 120 type 2 diabetic patients and 63 patients with maturity-onset diabetes of the young using denaturing high-performance liquid chromatography. 15504981 2004