Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
An adenine insertion in exon 6 of human GP6 generates a truncated protein associated with a bleeding disorder in four Chilean families.
|
23815599 |
2013 |
Glycoprotein VI deficiency
|
0.600 |
GermlineCausalMutation
|
disease |
ORPHANET |
A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder.
|
19552682 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
GeneticVariation
|
disease |
UNIPROT |
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations.
|
19549989 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
GeneticVariation
|
disease |
UNIPROT |
A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder.
|
19552682 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
GermlineCausalMutation
|
disease |
ORPHANET |
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations.
|
19549989 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations.
|
19549989 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder.
|
19552682 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations.
|
19549989 |
2009 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion.
|
12738669 |
2003 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo.
|
12515812 |
2003 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CLINGEN |
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
|
10961879 |
2000 |
Glycoprotein VI deficiency
|
0.600 |
Biomarker
|
disease |
CTD_human |
|
|
|
Finding of Mean Corpuscular Hemoglobin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
Myocardial Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Platelet GPVI surface expression is enhanced following acute ischemic events like myocardial infarction and cerebral stroke, serves as an imminent diagnostic tool independent of markers of tissue necrosis, and is associated with poor prognosis.
|
27753514 |
2017 |
Platelet mean volume determination (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Reticulocyte count (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Platelet Component Distribution Width Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Myocardial Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Increased GPVI levels are associated with poor clinical outcome and are an early indicator for imminent myocardial infarction in patients with chest pain.
|
24553806 |
2014 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Also, treatment of mice undergoing experimental myocardial infarction with αCD133-GPVI-labeled progenitor cells reduces infarction size and preserves myocardial function.
|
22448969 |
2012 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The impact of platelet collagen receptor polymorphisms in the pathogenesis of myocardial infarction at young age remains unknown.
|
22627583 |
2012 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A significant association between GP VI 13254C allele carriers and premature MI was found (p=0.025).
|
19786296 |
2010 |
Platelet aggregation
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.
|
20526338 |
2010 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The combined ThrThr/TT haplotype of GPIbalpha as well as the AA genotype of GPIV seem to decrease the risk of fatal MI among men during early middle-age.
|
17619827 |
2008 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our preliminary data suggests that platelet collagen receptor density, when measured directly, may be related to prior myocardial infarction.
|
15874887 |
2005 |