Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 Biomarker group BEFREE Pituitary adenylate cyclase activating polypeptide (PACAP, <i>Adcyap1</i>) is a neuromodulator implicated in anxiety, metabolism and reproductive behavior. 29905528 2018
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 Biomarker group BEFREE Urocortin1 neurons became over-active in CMVS-exposed PACAP knock out (KO) mice with MD180 history, suggesting the contribution of centrally projecting Edinger-Westphal nucleus to the reduced depression and anxiety level of stressed KO mice. 28450265 2017
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.030 Biomarker group BEFREE Further integration of epigenetic data and gene × environment interaction are promising approaches, as highlighted by FKPB5 and PACAP, early life trauma and stress-related anxiety disorders. 24234873 2013