ECSIT, ECSIT signaling integrator, 51295

N. diseases: 4; N. variants: 2
Disease: Bacterial Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.010 GeneticVariation group BEFREE Inactive forms of Rac, including the human Rac2(D57N) mutant, disrupted the TRAF6-ECSIT complex by sequestering TRAF6 and substantially diminished ROS production and enhanced susceptibility to bacterial infection. 26414765 2015