TLR8, toll like receptor 8, 51311

N. diseases: 122; N. variants: 8
Disease: Neuralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.020 Biomarker phenotype BEFREE The present study reveals a previously unknown role of TLR8 in the maintenance of neuropathic pain, suggesting that miR-21-TLR8 signaling may be potential new targets for drug development against this type of chronic pain. 30455267 2018
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.020 AlteredExpression phenotype BEFREE (https://doi.org/10.1084/jem.20180800) demonstrates that TLR8 activated by miR-21 controls neuropathic pain using a non-MyD88-dependent pathway. 30455266 2018