TLR8, toll like receptor 8, 51311

N. diseases: 122; N. variants: 8
Disease: Rhinovirus infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0276447
Disease: Rhinovirus infection
Rhinovirus infection 		0.030 GeneticVariation disease BEFREE TLR8 polymorphisms were associated with an increased risk and TLR7 polymorphisms with a decreased risk of recurrent rhinovirus infections (P = 0.02 for both). 28403045 2017
CUI: C0276447
Disease: Rhinovirus infection
Rhinovirus infection 		0.030 AlteredExpression disease BEFREE Expression of Toll-like receptor (TLR) 3, TLR7, TLR8, retinoic acid-inducible gene I (RIG-I), melanoma differentiation-associated gene 5 (MDA-5), TIR domain-containing adapter-inducing IFN-β (TRIF), myeloid differentiation primary response gene 88 (MyD88), caspase recruitment domain adaptor inducing IFN-β (CARDIF), IL-1 receptor-associated kinase 4 (IRAK4), IκB kinase β (IKKB), IκB kinase ι (IKKI), interferon regulatory factors 3 and 7, and rhinovirus induction of expression of the virus-inducible molecules TLR3, TLR7, RIG-I, and MDA-5 were not impaired in these interferon-deficient BAL cells in asthmatic patients. 22657407 2012
CUI: C0276447
Disease: Rhinovirus infection
Rhinovirus infection 		0.030 Biomarker disease BEFREE The differences in the gene expression of MDA-5, RIG-1, TLR-7, and TLR-8 were more evident in infants with RSV infection than in those with bocavirus or rhinovirus infection. 19386802 2009