NOL7, nucleolar protein 7, 51406

N. diseases: 7; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE Here we demonstrate that NOL7 is an mRNA-binding protein that must localize to the nucleoplasm to exert its antiangiogenic and tumor suppressive effects. 23085760 2013
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE In this study, we show that the RB tumor suppressor gene (RB) positively regulates NOL7 at the transcriptional level by recruiting transcription factors and transcription machinery proteins to its promoter region. 23308053 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE We have previously demonstrated that reintroduction of NOL7 into CC cells altered the angiogenic phenotype and suppressed tumor growth in vivo by 95%. 22123719 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. 16205646 2006
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.020 AlteredExpression disease BEFREE Endogenous NOL7 mRNA and protein expression in CC cell lines were significantly decreased in 46% of the CC cell lines. 22123719 2012
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 AlteredExpression disease BEFREE Endogenous NOL7 mRNA and protein expression in CC cell lines were significantly decreased in 46% of the CC cell lines. 22123719 2012
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.020 AlteredExpression disease BEFREE Endogenous NOL7 mRNA and protein expression in CC cell lines were significantly decreased in 46% of the CC cell lines. 22123719 2012
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.020 Biomarker disease BEFREE NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. 16205646 2006
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 Biomarker disease BEFREE NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. 16205646 2006
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.020 Biomarker disease BEFREE NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. 16205646 2006
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 AlteredExpression group BEFREE This loss of NOL7 expression is also observed in RB-deficient human malignancies. 23308053 2012
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.010 AlteredExpression group BEFREE Using cervical cancer as a model of investigation, we have previously shown that loss of NOL7 mRNA and protein expression is observed as early as the premalignant phase. 23308053 2012
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		0.010 AlteredExpression disease BEFREE In this study, we show that the RB tumor suppressor gene (RB) positively regulates NOL7 at the transcriptional level by recruiting transcription factors and transcription machinery proteins to its promoter region. 23308053 2012