NOL7, nucleolar protein 7, 51406

N. diseases: 7; N. variants: 0
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE Here we demonstrate that NOL7 is an mRNA-binding protein that must localize to the nucleoplasm to exert its antiangiogenic and tumor suppressive effects. 23085760 2013
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE In this study, we show that the RB tumor suppressor gene (RB) positively regulates NOL7 at the transcriptional level by recruiting transcription factors and transcription machinery proteins to its promoter region. 23308053 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE We have previously demonstrated that reintroduction of NOL7 into CC cells altered the angiogenic phenotype and suppressed tumor growth in vivo by 95%. 22123719 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. 16205646 2006