PDE4A, phosphodiesterase 4A, 5141

N. diseases: 168; N. variants: 3
Disease: Cardiovascular Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE There is significant increasing interest in phosphodiesterase-4 (PDE4) inhibition in treatment of cardiovascular diseases. 28836502 2018
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE The anti-inflammatory and vasodilator properties of PDE4 inhibitors make them suitable for treatment of stroke and cardiovascular disease. 26671126 2015
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE This study identifies PDE4 as a central node in the signaling network that mediates platelet-neutrophil adhesion and suggests that pharmacological inhibition of PDE4 may represent a novel therapeutic avenue for the treatment of cardiovascular disease. 24925970 2014