PDE4A, phosphodiesterase 4A, 5141

N. diseases: 168; N. variants: 3
Disease: Bronchitis, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008677
Disease: Bronchitis, Chronic
Bronchitis, Chronic 		0.020 GeneticVariation disease BEFREE Currently, the selective PDE4 inhibitor roflumilast is an approved add-on treatment for patients with severe chronic obstructive pulmonary disease with chronic bronchitis and a history of frequent exacerbations. 31664853 2020
CUI: C0008677
Disease: Bronchitis, Chronic
Bronchitis, Chronic 		0.020 Biomarker disease BEFREE In recent last years, the first phosphodiesterase 4 (PDE4) inhibitor, roflumilast, was approved as a treatment to reduce the risk of exacerbations in stable and severe COPD associated with chronic bronchitis and a history of exacerbations. 28201975 2017