PDE4A, phosphodiesterase 4A, 5141

N. diseases: 168; N. variants: 3
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 Biomarker disease BEFREE PDE4 inhibition by rolipram resulted in a positive inotropic effect and might serve as a target for developing agents for the treatment of heart failure in clinical settings. 30967774 2019
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 Biomarker disease BEFREE Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure. 29939224 2019