MTFP1, mitochondrial fission process 1, 51537

N. diseases: 6; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 AlteredExpression group BEFREE In this study, we first evaluated the expression of MTFP1 in 12-paired OSCC tumor and peritumor tissues. 31814213 2020
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.020 Biomarker phenotype BEFREE Collectively, our study demonstrates that MTFP1 plays a critical oncogenic role in OSCC carcinogenesis, which may serve as a potential therapeutic target in the treatment of this malignance.This article is protected by copyright.All rights reserved. 31814213 2020
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.020 Biomarker disease BEFREE Together, these results identify a HIF-1α/miR-668/MTP18 axis that may have potential as a therapeutic target for AKI. 30418172 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.020 Biomarker disease BEFREE MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury. 30325740 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 AlteredExpression group BEFREE MTP18 expression was evaluated by qRT-PCR and western blot analysis in 20 paired tumor and peritumor tissues. 30237394 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.020 Biomarker phenotype BEFREE MTP18 plays a pivotal oncogenic role in hepatocellular carcinogenesis; its overexpression may serve as a novel prognostic factor and a therapeutic target in HCC. 30237394 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.010 AlteredExpression disease BEFREE In this study, we first evaluated the expression of MTFP1 in 12-paired OSCC tumor and peritumor tissues. 31814213 2020
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.010 Biomarker phenotype BEFREE Functional experiments revealed that MTP18 promoted both the growth and metastasis of HCC cells by inducing the progression of cell cycle, epithelial to mesenchymal transition (EMT) and production of MMP-9, and suppressing cell apoptosis. 30237394 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.010 Biomarker disease BEFREE Functional experiments revealed that MTP18 promoted both the growth and metastasis of HCC cells by inducing the progression of cell cycle, epithelial to mesenchymal transition (EMT) and production of MMP-9, and suppressing cell apoptosis. 30237394 2018