SCLY, selenocysteine lyase, 51540

N. diseases: 161; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.040 GeneticVariation disease BEFREE Network analysis was applied on 955 patients with anorexia nervosa (AN; 631 restricting-type [ANR] and 324 binge eating-/purging-type [ANBP]), assessed with Symptom Check-List 90 (SCL-90), Eating Disorder Inventory (EDI), and Tridimensional Personality Questionnaire. 30062717 2019
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.040 GeneticVariation disease BEFREE There were significant differences in the global indices of the SCL-90R inventory between the three ED groups (Anorexia Nervosa (AN), Bulimia Nervosa (BN) and binge-eating disorder; ANOVA-p < 0.05). 29879886 2018
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.040 GeneticVariation disease BEFREE Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs. short allele), C-616G and C-521 T] and a variable number of tandem repeats (VNTR) in exon 3 (7R vs. non-7R allele). 29455021 2018
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.040 GeneticVariation disease BEFREE Haplotype <i>*6</i> in <i>KCTD15</i> was more frequent in controls (OR = 0.40 [0.20-0.80], <i>p</i> = .009 for anorexia nervosa), while haplotype <i>*4</i> in <i>TFAP2B</i> affected all three scales of the SCL-90R inventory in BN patients (<i>p</i> ≤ .01). 28948079 2017