SCLY, selenocysteine lyase, 51540

N. diseases: 161; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Individuals were assessed cross-sectionally for depression (PHQ-9), anxiety (GAD-7), post-traumatic stress disorder symptoms (PDS), somatic syndrome (SCL-90-R), alcohol dependence (ICD-10), functional impairment (PDS life functioning section), and self-perceived general physical health (SF-36). 31463614 2020
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE The Hopkins Symptom Checklist in 25 items (HSCL-25) helps to assess anxiety and depression in Primary Care. 30946774 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE The comparison of the patient and control groups based on SCL-90-R findings demonstrated that the patient group scores in somatization, anxiety (p = 0.000), depression (p = 0.003), anger (p = 0.02), interpersonal sensitivity (p = 0.006), phobia (p = 0.001), paranoid thoughts (p = 0.012), psychosis (p = 0.031) subscales and additional subscale (p = 0.014) and general symptom index (p = 0.001) scores were higher. 30472336 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Statistically higher SCL-90-R scores were found in active patients for obsessive-compulsive disorder (P = 0.026), depression (P = 0.013), anxiety (P = 0.013), phobic anxiety (P = 0.002), psychoticism (P = 0.007), global severity index (GSI) (P = 0.005) and positive symptom total (PST) (P = 0.001). 30689871 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Our region-of-interest results show a significant (<i>p</i> = 0.042, FWE cluster-level corrected) positive correlation of SCL-90-R scores for depression and a left hippocampus cluster. 31354542 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE The Symptom Checklist-90-Revised (SCL-90-R) was used to assess global psychological distress with a summary score termed Global Severity Index (GSI) and single psychological disorders including depression (DEP) and anxiety (ANX). 29246564 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE All abbreviated forms were strongly correlated with the SCL-90-R for general psychopathology (r = 0.93-0.99), depression (r = 0.89-0.95), anxiety (r = 0.97-0.98), psychosis (r = 0.95-0.99), and obsessive-compulsive symptoms (r = 0.97). 31665694 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE The primary outcome measure was severity of PTSD-symptoms (Harvard Trauma Questionnaire (HTQ)) and secondary outcome measures were depression and anxiety symptoms (Hopkins Symptom Checklist-25 (HSCL-25), Hamilton Depression and Anxiety rating scales (HAM-D, HAM-A)), somatisation (somatisation items of SCL-90 (SI-SCL-90)), quality of life (WHO-5-Well-being Index (WHO-5)) and functioning (Sheehan Disability Scale (SDS), Global Assessment of Functioning (GAF-F, GAF-S)). 30791342 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Moreover, compared with the short-term prisoners, mindfulness training was more effective on the long-term prisoners in mindfulness level (<i>p</i> < .05), SCL-90 (<i>p</i> < .001), anxiety (<i>p</i> < .05), depression (<i>p</i> < .05), aggression (<i>p</i> < .05), total mood disturbance (<i>p</i> < .0l), and perceived stress (<i>p</i> < .0l). 31043102 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE The measure of depression used is the Hopkins Symptom Checklist-10 (HSCL-10) inventory. 30999796 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Demographics, lung function, anxiety (anxiety subscale of the 90-item symptom checklist (SCL-90-A)), depression (Beck depression inventory for primary care (BDI-PC)), exercise tolerance (six-minute walking distance test (6MWD)), and health status (Nijmegen clinical screening instrument (NCSI)) were assessed before and after a 12-week PR programme. 31434343 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE We found differences between the eutocic and instrumental delivery groups in the SCL-90-R subscales somatisation (t = 6.98; p = 0.01), anxiety (t = 3.42; p < 0.05), depression (t = 5.20; p < 0.02) and psychoticism (t = 5.28; p < 0.01), and in the general indices global severity index (t = 5.57; p < 0.05) and positive symptoms (t = 5.21; p < 0.01). 31254963 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Symptoms of anxiety and depression were assessed by the Hopkins Symptom Checklist-25 (HSCL-25), somatization was assessed by the Somatization Subscale of the Symptom-Checklist-90 (SCL-90), and the number of witnessed and experienced trauma was assessed by the Posttraumatic Diagnostic Scale (PDS/HTQ). 31088419 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE In this longitudinal study, 27 lung transplant recipients were prospectively examined for psychological distress (Symptom Checklist short version-9; SCL-K-9), health-related quality of life (EuroQOL five dimensions questionnaire; EQ-5D), depression (HADS-Depression scale), and socio-demographic and medical outcomes at two weeks, three months, six months and three years following LTx. 30961347 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE We therefore aim to investigate the change in screening status and in severity of depression and distress symptoms between three and eight months postpartum among a sample of Sudanese women using the Edinburgh Postnatal Depression Scale (EPDS) and a locally used tool: the 10-items Hopkins Symptoms Checklist (HSCL-10). 30089466 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE The PSS-4 scores showed a positive correlation with the SCL 90-R anxiety and depression scales. 29434563 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE A wide neuropsychiatric battery was employed including the following: symptoms checklist 90-R (SCL-90-R), Toronto alexithymia scale (TAS-20), Hamilton anxiety rating scale (HAMA), Beck depression inventory (BDI II), dissociative experiences scale (DES), traumatic experience checklist (TEC), somatoform dissociation questionnaire (SDQ-20), and temperament and character inventory-revised (TCI-R). 29092782 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE The results from the current study supported the use of the SCL-10 and WHO-5 as potential PROMs to capture symptom burden and quality of life within groups of people with anxiety or depression undergoing psychotherapy treatment. 29546787 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Individual's completed measures of perfectionism (Frost-MPS), Emotional Inhibition (EIS), Depression (BDI-II), Anxiety (STAI-Y), Global symptoms (SCL-90-R), and interpersonal problems (IIP-32). 29621675 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Significant negative or positive correlations were observed between GH-IGF-1 concentrations and impairments on several EDI-2 subscales (drive for thinness, body dissatisfaction, interoceptive awareness, sense of ineffectiveness, interpersonal distrust, maturity fear) and on SCL-90 subitems (depression, hostility, obsessivity compulsivity, anxiety), suggesting a possible hormonal modulatory effect on specific aspects of ED psychopathology. 29179911 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Among adolescents, those on EFV had lower scores on depression (HADS (Cohen's D: 0.3; P = 0.02) and SCL-90 (Cohen's D: 0.1; P = 0.02). 29220120 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Mothers reported symptoms of anxiety and depression three times during pregnancy (at 13.3 ± 1.1, 20.2 ± 1.5, and 33.8 ± 1.5 weeks of pregnancy, respectively) using the anxiety subscale of the Symptom Checklist (SCL-90), the Spielberger State and Trait Anxiety Inventory (STAI), and the Edinburgh Postnatal Depression Scale (EPDS). 29902667 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 AlteredExpression phenotype BEFREE CD patients experienced high levels of depression (HADS Depression 35.2% <i>p</i> = 0.034; SCL-90-R mean 1.39 <i>p</i> < 0.001), somatisation (SCL-90-R mean 1.04 <i>p</i> < 0.001), obsessive-compulsive symptoms (SCL-90-R mean 1.2 <i>p</i> < 0.001), and global severity (SCL-90-R mean 1.15 <i>p</i> < 0.001). 30127753 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 Biomarker phenotype BEFREE Among 540 adults, anxiety was measured by the Symptom Checklist 90-R (SCL-90R) anxiety subscale, and detailed demographics, epilepsy localization, and depression scores (SCL-90R) were collected. 29908386 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.100 GeneticVariation phenotype BEFREE Anxiety and depression were measured using the HSCL-25, and condom use and sexual partner concurrency were assessed through self-report. 29156358 2018