SCLY, selenocysteine lyase, 51540

N. diseases: 161; N. variants: 2
Disease: Adult Erythroleukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2347748
Disease: Adult Erythroleukemia
Adult Erythroleukemia 		0.020 Biomarker disease BEFREE ChIP-seq analyses in a human erythroleukemia cell line showed that LYL1 exclusively bound a small subset of SCL targets including <i>GATA1.</i> Together, these data show for the first time that <i>Lyl1</i> can maintain primitive erythropoiesis. 30185409 2018
CUI: C2347748
Disease: Adult Erythroleukemia
Adult Erythroleukemia 		0.020 Biomarker disease BEFREE mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. 10688671 2000