Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345946
Disease: Squamous cell carcinoma of trachea
Squamous cell carcinoma of trachea
0.010 GeneticVariation disease BEFREE Of 24 patients with actionable mutations, five were given genotype-matched drugs corresponding to actionable mutations: everolimus to PIK3CA mutation in parotid carcinosarcoma (partial response) and tracheal squamous cell carcinoma (stable disease; 21% reduction), sorafenib to PDGFRA mutation in auditory canal adenocarcinoma (partial response), sorafenib to BRAF mutation in microcytic adnexal carcinoma (progressive disease), and afatinib to ERBB2 mutation in esophageal adenocarcinoma (progressive disease). 27105424 2016