Disease: Childhood Gastrointestinal Stromal Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4086159
Disease: Childhood Gastrointestinal Stromal Tumor
Childhood Gastrointestinal Stromal Tumor 		0.020 AlteredExpression disease BEFREE Imatinib has exceptional activity in controlling gastrointestinal stromal tumor (GIST) due to inhibition of the constitutively active conformation of KIT and PDGFRA which is found in the majority of patients with GIST. 21140148 2011
CUI: C4086159
Disease: Childhood Gastrointestinal Stromal Tumor
Childhood Gastrointestinal Stromal Tumor 		0.020 AlteredExpression disease BEFREE Gastrointestinal stromal tumor (GIST) is the most frequent sarcoma of the intestinal tract and often shows constitutive activation of either the KIT or PDGFRA receptor tyrosine kinases because of gain-of-function mutation. 18076015 2008