MED15, mediator complex subunit 15, 51586

N. diseases: 57; N. variants: 1
Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 Biomarker group BEFREE Mediator complex subunit 15 (MED15) is a coactivator involved in the regulated transcription of RNA polymerase II-dependent genes and serves an oncogenic role in numerous types of cancer. 29556287 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 Biomarker group BEFREE The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy. 30127891 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 AlteredExpression group BEFREE Expression levels of TIG1 were significantly low in primary carcinomas and cancer cell lines compared to those of normal tissues. 19806788 2009
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 PosttranslationalModification group BEFREE We examined TIG1 methylation and expression status in 53 human cancer cell lines and 74 primary tumors, including leukemia and head and neck, breast, colon, skin, brain, lung, and prostate cancer. 15059893 2004