DisGeNET - a database of gene-disease associations

LSR, lipolysis stimulated lipoprotein receptor, 51599

N. diseases: 44; N. variants: 3

Disease: Alzheimer's Disease ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.020

Biomarker

disease

BEFREE

The LSR marker showed better prediction of conversion to AD than NHV.

30451343

2019

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.020

GeneticVariation

disease

BEFREE

Interestingly, the interaction of LSR polymorphisms with APOE non-ε4 alleles increased AD risk.

29858039

2018