PDYN, prodynorphin, 5173

N. diseases: 197; N. variants: 13
Disease: Opiate Addiction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.050 GeneticVariation disease BEFREE Association between prodynorphin gene polymorphisms and opioid dependence susceptibility: a meta-analysis. 31510971 2019
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.050 GeneticVariation disease BEFREE A significant association between opioid dependence and SNP rs910080 of PDYN (P=.0217) was detected, but there was no association for SNPs rs199774 and rs1022563. 28656735 2018
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.050 GeneticVariation disease BEFREE These data show that polymorphisms in PDYN are associated with opioid addiction in EAs and provide further evidence that these risk variants may be more relevant in females. 22443215 2012
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.050 GeneticVariation disease BEFREE Therefore, SNPs in PDYN are significantly associated with the risk of developing opioid dependence; however, this effect may only be seen in females. 19298317 2009
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.050 GeneticVariation disease BEFREE A functional prodynorphin promoter polymorphism and opioid dependence. 16314761 2005