|
Kidney Failure, Chronic
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.
|
31178898 |
2019 |
|
Malignant Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Despite limited power, there was a trend toward improved OS for the 13-CRA arm (HR, 0.75; P = .14), particularly among patients whose index tumor was surgically excised (N = 26; HR, 0.50; P = .057) and among women (N = 39; HR, 0.44; P = .065) and never/former smokers (N = 129; HR, 0.61; P = .055), with a median follow-up of 16 years.
|
28786105 |
2017 |
|
Primary malignant neoplasm
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Tachycardia, Ventricular
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Since a large number of triterpenoid compound has marked anticancer effects toward various types of cancer cell lines in vitro, this study was carried out to investigate the anticancer effect of CRA in human gastric cancer cell line BGC823 cells and the underlying apoptotic mechanism of CRA was examined in BGC823 cell lines.
|
28506699 |
2017 |
|
Heart failure
|
0.020 |
Biomarker
|
disease |
BEFREE |
RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.
|
22939879 |
2013 |
|
Congestive heart failure
|
0.020 |
Biomarker
|
disease |
BEFREE |
RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.
|
22939879 |
2013 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
CRA-026440 parenterally given to mice harboring HCT116 or U937 human tumor xenografts resulted in a statistically significant reduction in tumor growth.
|
16891455 |
2006 |
|
Obesity
|
0.020 |
Biomarker
|
disease |
BEFREE |
We aimed to evaluate whether obesity was associated with a certain clinicopathologic characteristics of metachronous CRA.
|
29079785 |
2017 |
|
Obesity
|
0.020 |
Biomarker
|
disease |
BEFREE |
We adjusted the CRA approach to purely capture obesity (BMI ≥ 30 kg/m²).
|
30274272 |
2018 |
|
Non-alcoholic Fatty Liver Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
These results demonstrated that CRA might protect the liver injury by its anti-oxidant effect, which could be a potential therapeutic agent of NAFLD.
|
29803928 |
2018 |
|
Non-alcoholic Fatty Liver Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
Since a large number of triterpenoid compound has marked anticancer effects toward various types of cancer cell lines in vitro, this study was carried out to investigate the anticancer effect of CRA in human gastric cancer cell line BGC823 cells and the underlying apoptotic mechanism of CRA was examined in BGC823 cell lines.
|
28506699 |
2017 |
|
Cheilitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The main 13-CRA related toxicities were dry skin and cheilitis.
|
28786105 |
2017 |
|
Congenital chromosomal disease
|
0.010 |
Biomarker
|
group |
BEFREE |
Thirteen patients had morphologic and cytogenetic evaluation of marrow cells before 13-CRA treatment, and with one exception, marrow morphologic and cytogenetic abnormalities persisted following 13-CRA administration.
|
3514807 |
1986 |
|
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
ATP-CRA tailored-chemotherapy has the potential to provide a survival benefit in resectable advanced CRC.
|
31384612 |
2019 |
|
Cardiac Arrest
|
0.010 |
Biomarker
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Hyperglycemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
In conclusion, we demonstrated that NCRAE, a natural extract of chicory (Cichorium intybus) rich in CRA and CQAs improves glucose tolerance and reduces the basal hyperglycemia in STZ diabetic rats.
|
29325917 |
2018 |
|
Macular Edema, Cystoid
|
0.010 |
Biomarker
|
disease |
BEFREE |
To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema caused by CRVO.
|
30347030 |
2018 |
|
Opioid withdrawal
|
0.010 |
Biomarker
|
disease |
BEFREE |
Despite significantly greater improvement by the OPU group, they did not improve to the level of the MAPU group over 12 months, suggesting that they may benefit from A-CRA continuing care up to 12 months, medication to address opioid withdrawal and craving, and the inclusion of opioid-focused A-CRA procedures.
|
28282523 |
2017 |
|
Rhabdomyosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although Surv.m-CRA efficiently replicated and potently induced cell death in all populations of rhabdomyosarcoma cells, the cytotoxic effects were more pronounced in RSC-enriched or RSC-purified cells than in RSC-exiguous or progeny-purified cells.
|
24467821 |
2014 |
|
Ventricular Fibrillation
|
0.010 |
Biomarker
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Central retinal vein occlusion
|
0.010 |
Biomarker
|
disease |
BEFREE |
To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema caused by CRVO.
|
30347030 |
2018 |
|
Childhood Rhabdomyosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although Surv.m-CRA efficiently replicated and potently induced cell death in all populations of rhabdomyosarcoma cells, the cytotoxic effects were more pronounced in RSC-enriched or RSC-purified cells than in RSC-exiguous or progeny-purified cells.
|
24467821 |
2014 |