|
Kidney Failure, Chronic
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.
|
31178898 |
2019 |
|
Malignant Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Non-alcoholic Fatty Liver Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Primary malignant neoplasm
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Obesity
|
0.020 |
Biomarker
|
disease |
BEFREE |
We adjusted the CRA approach to purely capture obesity (BMI ≥ 30 kg/m²).
|
30274272 |
2018 |
|
Non-alcoholic Fatty Liver Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
These results demonstrated that CRA might protect the liver injury by its anti-oxidant effect, which could be a potential therapeutic agent of NAFLD.
|
29803928 |
2018 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Since a large number of triterpenoid compound has marked anticancer effects toward various types of cancer cell lines in vitro, this study was carried out to investigate the anticancer effect of CRA in human gastric cancer cell line BGC823 cells and the underlying apoptotic mechanism of CRA was examined in BGC823 cell lines.
|
28506699 |
2017 |
|
Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Despite limited power, there was a trend toward improved OS for the 13-CRA arm (HR, 0.75; P = .14), particularly among patients whose index tumor was surgically excised (N = 26; HR, 0.50; P = .057) and among women (N = 39; HR, 0.44; P = .065) and never/former smokers (N = 129; HR, 0.61; P = .055), with a median follow-up of 16 years.
|
28786105 |
2017 |
|
Obesity
|
0.020 |
Biomarker
|
disease |
BEFREE |
We aimed to evaluate whether obesity was associated with a certain clinicopathologic characteristics of metachronous CRA.
|
29079785 |
2017 |
|
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
Since a large number of triterpenoid compound has marked anticancer effects toward various types of cancer cell lines in vitro, this study was carried out to investigate the anticancer effect of CRA in human gastric cancer cell line BGC823 cells and the underlying apoptotic mechanism of CRA was examined in BGC823 cell lines.
|
28506699 |
2017 |
|
Heart failure
|
0.020 |
Biomarker
|
disease |
BEFREE |
RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.
|
22939879 |
2013 |
|
Congestive heart failure
|
0.020 |
Biomarker
|
disease |
BEFREE |
RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.
|
22939879 |
2013 |
|
Heart failure
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Of the 17 mRNA splicing factors upregulated in heart failure, RBM25 and LUC7L3 were sufficient to explain the increase in truncated forms and the reduction in full-length Na+ channel transcript.
|
21859973 |
2011 |
|
Congestive heart failure
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Of the 17 mRNA splicing factors upregulated in heart failure, RBM25 and LUC7L3 were sufficient to explain the increase in truncated forms and the reduction in full-length Na+ channel transcript.
|
21859973 |
2011 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
CRA-026440 parenterally given to mice harboring HCT116 or U937 human tumor xenografts resulted in a statistically significant reduction in tumor growth.
|
16891455 |
2006 |
|
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
ATP-CRA tailored-chemotherapy has the potential to provide a survival benefit in resectable advanced CRC.
|
31384612 |
2019 |
|
Adenoma of large intestine
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lifestyle modification plays a key role in nonalcoholic fatty liver disease (NAFLD) and colorectal adenoma and/or cancer (CRA/CRC) development.
|
30791768 |
2019 |
|
Cardiac Arrest
|
0.010 |
Biomarker
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Hyperglycemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
In conclusion, we demonstrated that NCRAE, a natural extract of chicory (Cichorium intybus) rich in CRA and CQAs improves glucose tolerance and reduces the basal hyperglycemia in STZ diabetic rats.
|
29325917 |
2018 |
|
Macular Edema, Cystoid
|
0.010 |
Biomarker
|
disease |
BEFREE |
To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema caused by CRVO.
|
30347030 |
2018 |
|
Ventricular Fibrillation
|
0.010 |
Biomarker
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Tachycardia, Ventricular
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The cardiac rhythm as primary origin of the CRA was ventricular fibrillation (VF) in 16 patients (61.5%), asystole in 8 patients (34.6%) and ventricular tachycardia (VT) in one patient (3.8%).
|
29275174 |
2018 |
|
Central retinal vein occlusion
|
0.010 |
Biomarker
|
disease |
BEFREE |
To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema caused by CRVO.
|
30347030 |
2018 |
|
Macular retinal edema
|
0.010 |
Biomarker
|
disease |
BEFREE |
To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema caused by CRVO.
|
30347030 |
2018 |
|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
JMJD6 has been reported to be over-expressed in oral, breast, lung, and colon cancers and plays important roles in regulation of transcription through interactions with transcription regulator BRD4, histones, U2AF65, Luc7L3, and SRSF11.
|
29176719 |
2017 |