Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
The association of platelet endothelial cell adhesion molecule 1 (PECAM1), hypoxia-inducible factor 1 subunit alpha (HIF1A), and KIAA1462 in myocardial infarction (MI) was investigated.
|
30678728 |
2019 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Tracer uptake in damaged tissue correlated with the amount of CD68-positive macrophages at 7 days after MI, and CD31-positive endothelial cells at 7 days and 4 weeks after MI.
|
27914007 |
2018 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Expression of both the endothelial marker CD-31 and α-smooth muscle actin was markedly lower in the knockout than in wildtype mice at 7 days after MI.
|
28453729 |
2017 |
Myocardial Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Compared with MI group, SG treatment dose-dependently improved cardiac hemodynamic function, attenuated infarct size, increased microvessel density, and increased the expression of PECAM-1/CD31 and VEGF.
|
28757887 |
2017 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunostaining of CD31 and matrigel plug assay were performed to detect angiogenesis in a mouse myocardial infarction (MI) model.
|
28249798 |
2017 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Moreover, angiogenesis was also examined using the endothelial markers CD31 both at early (day 7) and late stages (day 28) after MI, and ATM haplodeficiency reduced angiogenesis after MI.
|
28724653 |
2017 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In order to find new informative predictors of myocardial infarction, we performed an analysis of genotype frequencies of polymorphic markers of SELE (rs2076059, 3832T > C), SELP (rs6131, S290 N), SELL (rs1131498, rs1131498" genes_norm="6402">F206L), ICAM1 (rs5498, K469E), VCAM1 (rs3917010, c.928 + 420A > C), PECAM1 (rs668, V125L), VEGFA (rs35569394, -2549(18)I/D), CCL2 (rs1024611, -2518A > G), NOS3 (rs1799983, E298D), and DDAH1 (rs669173, c.303 + 30998A > G) genes in the group of Russian men with myocardial infarction (N = 315) and the control group of corresponding ethnicity, gender, and age (N = 286).
|
26662939 |
2016 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Of the chosen polymorphisms, two (Leu125Val PECAM1 and A1/A2 FVII) are related to myocardial infarction and two (C677T MTHFR and 5A/6A MMP3) to advanced stenosis in arterial vessels (> 75%).
|
23274712 |
2013 |
Myocardial Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Medline, HuGE Navigator and SCOPUS Library databases were searched to identify case-control studies which examined the association of SNPs in PECAM-1 and MI.
|
23906939 |
2013 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The 643R allele of R643G polymorphism (also known as R670G in the premature protein) in PECAM-1 has been associated with risk of myocardial infarction (MI), while the 643G allele has been associated with risk of coronary artery stenosis (CAS).
|
15488875 |
2004 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The PECAM1 Leu125Val and Ser563Asn polymorphisms may increase the risk of atherosclerosis but not necessarily of MI.
|
14575520 |
2003 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Stratification analysis of the patients showed that the associations of these PECAM-1 genotypes with myocardial infarction were preferentially found in male and younger patients (age of onset of myocardial infarction less than 60 years).
|
11795274 |
2001 |