|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Ectopic expression of this truncated domain significantly suppressed G1/S-phase transition, cellular proliferation, and tumour formation of RK3E-p53(R175H) /Rsf-1/cyclin E1 cells.
|
23378270 |
2013 |
|
Age at menarche
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Malignant neoplasm of ovary
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma.
|
23378270 |
2013 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma.
|
23378270 |
2013 |
|
Malignant Neoplasms
|
0.060 |
GeneticVariation
|
group |
BEFREE |
Overexpression or amplification of the RSF1 gene has been associated with poor prognosis in various human cancers, including ovarian cancer.
|
24566868 |
2014 |
|
Ovarian Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma.
|
23378270 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Rsf-1 knockout further enhanced the paclitaxel-mediated decrease in the volume and weight of the tumors in H460 cell xenograft mice.
|
29258089 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this report, we studied the biological roles of RSF-1 in oral squamous cell carcinoma (OSCC), a highly invasive neoplastic disease.
|
21514451 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this study, we found that hSNF2H was overexpressed in 32 % of glioma specimens. hSNF2H overexpression correlated with advanced tumor grade (p = 0.0338) and Rsf-1 positivity in glioma tissues (p = 0.016).
|
26666816 |
2016 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
In summary, amplification of these four putative oncogenes from 11q13 in early ovarian cancer is associated with a serous histology and in the case of EMSY and RSF1 a poor outcome.
|
18314909 |
2008 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
These data suggest that Rsf-1/HBXAP gene-transduced DCs may be a potential adjuvant immunotherapy for ovarian cancer in clinical applications.
|
20226169 |
2010 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
Taken together, these findings indicate an important role of Rsf-1 amplification in ovarian cancer.
|
16172393 |
2005 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer.
|
19190325 |
2009 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
To further elucidate the role of Rsf-1 in ovarian cancer, we studied Rsf-1 immunoreactivity in 294 ovarian tumors of various histologic types.
|
16938522 |
2006 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
In summary, amplification of these four putative oncogenes from 11q13 in early ovarian cancer is associated with a serous histology and in the case of EMSY and RSF1 a poor outcome.
|
18314909 |
2008 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer.
|
19190325 |
2009 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
These data suggest that Rsf-1/HBXAP gene-transduced DCs may be a potential adjuvant immunotherapy for ovarian cancer in clinical applications.
|
20226169 |
2010 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
To further elucidate the role of Rsf-1 in ovarian cancer, we studied Rsf-1 immunoreactivity in 294 ovarian tumors of various histologic types.
|
16938522 |
2006 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
Taken together, these findings indicate an important role of Rsf-1 amplification in ovarian cancer.
|
16172393 |
2005 |
|
Malignant Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Rsf-1 (HBXAP) has been reported as an amplified gene in human cancer, including the highly aggressive ovarian serous carcinoma.
|
20923775 |
2010 |
|
Malignant Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Hepatitis B virus x associated protein (HBXAP), as a subunit of chromatin remodeling and spacing factor, plays a critical role in cancer development through gene amplification.
|
23456648 |
2013 |
|
Malignant Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Our previous studies demonstrated requirement of Rsf-1 for cell survival in cancer cells, which contributed to tumour progression; however, its role in tumourigenesis has not yet been elucidated.
|
23378270 |
2013 |
|
ovarian neoplasm
|
0.060 |
Biomarker
|
disease |
LHGDN |
Taken together, these findings indicate an important role of Rsf-1 amplification in ovarian cancer.
|
16172393 |
2005 |
|
ovarian neoplasm
|
0.060 |
Biomarker
|
disease |
LHGDN |
We found that Rsf-1 was up-regulated in paclitaxel-resistant ovarian cancer cell lines, and Rsf-1 immunoreactivity in primary ovarian carcinoma tissues correlated with in vitro paclitaxel resistance.
|
19190325 |
2009 |
|
ovarian neoplasm
|
0.060 |
Biomarker
|
disease |
LHGDN |
In summary, amplification of these four putative oncogenes from 11q13 in early ovarian cancer is associated with a serous histology and in the case of EMSY and RSF1 a poor outcome.
|
18314909 |
2008 |