|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Positive RSF1 expression was associated with advanced tumour stage, high Gleason grade, lymph node metastasis (<i>p</i> < .0001 each), early biochemical recurrence (<i>p</i> < .0003) and more frequent in the ERG positive than in the ERG negative subset (88% versus 71%; <i>p</i> < .0001).
|
31687881 |
2020 |
|
Age at menarche
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The results demonstrated that a high expression level of RSF1 in RCC is associated with advanced tumor stages and a poor prognosis.
|
29467902 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Rsf-1 knockout further enhanced the paclitaxel-mediated decrease in the volume and weight of the tumors in H460 cell xenograft mice.
|
29258089 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this study, we found that hSNF2H was overexpressed in 32 % of glioma specimens. hSNF2H overexpression correlated with advanced tumor grade (p = 0.0338) and Rsf-1 positivity in glioma tissues (p = 0.016).
|
26666816 |
2016 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
There was a significant association between Rsf-1 overexpression and tumor stage (p = 0.0322), AFP (p = 0.0184), and tumor relapse (p = 0.0112).
|
24798976 |
2014 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, serum HBXAP DNA levels were not associated with patient age, gender, smoking status, histological type, or tumor size (p > 0.05).
|
23456648 |
2013 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Ectopic expression of this truncated domain significantly suppressed G1/S-phase transition, cellular proliferation, and tumour formation of RK3E-p53(R175H) /Rsf-1/cyclin E1 cells.
|
23378270 |
2013 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 overexpression was demonstrated in 101 cases (34.2%), and was significantly associated with advanced primary tumour (p<0.001), nodal metastasis (p=0.004), higher histological grades (p=0.001) and frequent mitoses (p<0.001).
|
22685262 |
2012 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, there was no correlation between Rsf-1 expression and patient age, peritoneal tumor dissemination, or overall survival.
|
21131837 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this report, we studied the biological roles of RSF-1 in oral squamous cell carcinoma (OSCC), a highly invasive neoplastic disease.
|
21514451 |
2011 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The above findings suggest that increased Rsf-1 expression and thus excessive RSF activity, which occurs in tumors harboring Rsf-1 amplification, can induce chromosomal instability likely through DDR.
|
20923775 |
2010 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 expression in tumor cells in effusions was analyzed for possible association with clinicopathologic parameters and survival.
|
16844205 |
2006 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 overexpression was observed in 25% of high-grade ovarian serous carcinomas and in only rare cases (<7%) of low-grade ovarian serous, ovarian endometrioid, and invasive breast carcinomas but not in any ovarian serous borderline tumors, ovarian clear cell carcinomas, ovarian mucinous carcinomas, intraductal carcinomas of the breast, and normal ovaries and breast tissues.
|
16938522 |
2006 |
|
Malignant neoplasm of ovary
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we further demonstrated that RSF1 expression inversely correlated with paclitaxel response in patients with ovarian cancer and the mouse xenograft model.
|
24566868 |
2014 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we further demonstrated that RSF1 expression inversely correlated with paclitaxel response in patients with ovarian cancer and the mouse xenograft model.
|
24566868 |
2014 |
|
Malignant neoplasm of ovary
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma.
|
23378270 |
2013 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Chromosome 11q13.5 containing RSF1 (HBXAP), a gene involved in chromatin remodelling, is amplified in several human cancers including ovarian carcinoma.
|
23378270 |
2013 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
These data suggest that Rsf-1/HBXAP gene-transduced DCs may be a potential adjuvant immunotherapy for ovarian cancer in clinical applications.
|
20226169 |
2010 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
These data suggest that Rsf-1/HBXAP gene-transduced DCs may be a potential adjuvant immunotherapy for ovarian cancer in clinical applications.
|
20226169 |
2010 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer.
|
19190325 |
2009 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer.
|
19190325 |
2009 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
In summary, amplification of these four putative oncogenes from 11q13 in early ovarian cancer is associated with a serous histology and in the case of EMSY and RSF1 a poor outcome.
|
18314909 |
2008 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
Biomarker
|
disease |
BEFREE |
In summary, amplification of these four putative oncogenes from 11q13 in early ovarian cancer is associated with a serous histology and in the case of EMSY and RSF1 a poor outcome.
|
18314909 |
2008 |
|
Malignant neoplasm of ovary
|
0.070 |
Biomarker
|
disease |
BEFREE |
To further elucidate the role of Rsf-1 in ovarian cancer, we studied Rsf-1 immunoreactivity in 294 ovarian tumors of various histologic types.
|
16938522 |
2006 |