PEG3, paternally expressed 3, 5178

N. diseases: 62; N. variants: 4
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Thus, mammalian imprinting utilizes Peg3/Pw1 to co-opt the Wnt pathway, thereby regulating development and glioma growth. 20064927 2010
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE In this study, we investigated methylation of an exonic CpG island in the promoter region and the expression of PEG3 gene in 20 glioma and 5 non-tumor tissue samples. 19367087 2009
CUI: C0017638
Disease: Glioma
Glioma 		0.050 PosttranslationalModification disease BEFREE We have previously reported that the epigenetic silencing of PEG3 expression in glioma cell lines is dependent on aberrant DNA methylation of an exonic CpG island. 15141944 2004
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE In this article, we report that the epigenetic silencing of PEG3 expression in glioma cell lines depends on aberrant DNA methylation of an exonic CpG island, suggesting that PEG3 contributes to glioma carcinogenesis in certain cases. 11398192 2001
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE Tumour suppressor activity of human imprinted gene PEG3 in a glioma cell line. 11260267 2001