PENK, proenkephalin, 5179

N. diseases: 124; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 Biomarker disease BEFREE Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability. 22683090 2012
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 Biomarker disease PSYGENET Cigarette smoking is common in cannabis users, but it was not associated to PENK SNPs as also validated in another cohort (N = 247 smokers, N = 312 non-smokers). 22745721 2012
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 Biomarker disease BEFREE Dopamine receptor D2 (DRD2) and proenkephalin (PENK) genes have been implicated in animal studies with cannabis exposure. 22745721 2012
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 Biomarker disease PSYGENET Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability. 22683090 2012
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 Biomarker disease PSYGENET Prenatal cannabis exposure was significantly associated with increased mu receptor expression in the amygdala, reduced kappa receptor mRNA in mediodorsal thalamic nucleus and reduced preproenkephalin expression in the caudal putamen. 16477274 2006
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.330 AlteredExpression disease BEFREE Prenatal cannabis exposure was significantly associated with increased mu receptor expression in the amygdala, reduced kappa receptor mRNA in mediodorsal thalamic nucleus and reduced preproenkephalin expression in the caudal putamen. 16477274 2006