PENK, proenkephalin, 5179

N. diseases: 124; N. variants: 5
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression group BEFREE Additionally, PENK expression was associated with tumor size, mitosis count per 50 high-power fields, and tumor rupture (<i>P</i><0.05). 31410059 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 PosttranslationalModification group BEFREE Of these, we newly identified GSTM2 and PENK as being genes that are hypermethylated in prostate cancer and that were simultaneously methylated in 40.9% of the tumors analyzed. 24961912 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker group BEFREE Several human tumour cell lines were screened for secretion of proenkephalin-derived peptides with an antiserum directed to its N-terminus, Met-enkephalin-Arg6,Phe7 and for proopiomelanocortin-derived peptides with an antiserum to beta-endorphin. 3382940 1988