Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020651
Disease: Hypotension, Orthostatic
Hypotension, Orthostatic
0.320 GeneticVariation phenotype BEFREE AIMS To investigate the influence of ABCB1 (1236-2677-3435) polymorphisms on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers. 21999196 2012
CUI: C0020651
Disease: Hypotension, Orthostatic
Hypotension, Orthostatic
0.320 Biomarker phenotype CTD_human Our results suggest that homozygosity for 3435T alleles of ABCB1 is a risk factor for occurrence of nortriptyline-induced postural hypotension (OR = 1.37, P = 0.042, 95% CI 1.01-1.86). 12082591 2002
CUI: C0020651
Disease: Hypotension, Orthostatic
Hypotension, Orthostatic
0.320 GeneticVariation phenotype BEFREE Our results suggest that homozygosity for 3435T alleles of ABCB1 is a risk factor for occurrence of nortriptyline-induced postural hypotension (OR = 1.37, P = 0.042, 95% CI 1.01-1.86). 12082591 2002