PHB, prohibitin, 5245

N. diseases: 177; N. variants: 8
Disease: Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis 		0.030 AlteredExpression disease BEFREE PHB Tg/Nrf2(-/-) mice exhibited increased activation of ERK during colitis. 23494124 2013
CUI: C0009319
Disease: Colitis
Colitis 		0.030 AlteredExpression disease BEFREE Genetic restoration of intestinal epithelial prohibitin 1 (PHB) levels during experimental colitis reduces the severity of disease through sustained epithelial antioxidant expression and reduced NF-κB activation. 20872832 2011
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE PHB transgenic mice exhibited decreased oxidative stress and colitis and increased Nrf2 messenger RNA expression, nuclear protein translocation, and DNA binding compared with wild-type littermates during colitis. 19327358 2009