PHB, prohibitin, 5245

N. diseases: 177; N. variants: 8
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease BEFREE In contrast, PHB knock-down sensitized melanoma cells to cisplatin and tunicamycin treatment. 28562344 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease BEFREE TCGA-RNAseq data obtained from 341 melanoma patient samples as well as a panel of melanoma cell lines were used in an expression correlation analysis between PHB1 and predicted miRNAs. miR-195 impact on PHB1 mRNA and protein levels and relevance of this regulation were investigated in UACC-62 and SK-MEL-5 melanoma lines by RT-qPCR and western blot, luciferase reporter and genetic rescue experiments. 29126391 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.030 GeneticVariation disease BEFREE Similarly, the prohibitin TT genotype increased melanoma risk in the crude and adjusted analyses (OR 2.40; 95% CI 1.10-5.26; P<0.05). 23624368 2013