PHB, prohibitin, 5245

N. diseases: 177; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.020 AlteredExpression disease BEFREE Thus, we evaluated the expression levels of PHB1 in experimental autoimmune encephalomyelitis (EAE), the animal model of MS and on MS patient's lymphocytes. 29242126 2018
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.020 Biomarker disease BEFREE Our observations suggest a pivotal role for the PHB-CRAF-MAPK signalling axis in regulating the polarization and pathogenicity of Th17 cells and unveil druggable targets in autoimmune disorders such as MS. 30049713 2018