PHB, prohibitin, 5245

N. diseases: 177; N. variants: 8
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 Biomarker disease BEFREE The present study provides an overview on the role played by PHB1, TGF-β and LH in ovarian cancer. 28427435 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 GeneticVariation disease BEFREE In the sub-group analysis, prohibitin 3' untranslated region C > T gene polymorphism and cancer risk appeared associated with the risk of breast cancer, but not ovarian cancer. 22994754 2012
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 AlteredExpression disease BEFREE Furthermore, silencing of the Phb1 gene expression may prove to be a valuable therapeutic approach for chemoresistant ovarian cancer by increasing sensitivity of cancer cells to apoptosis. 18183577 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 GeneticVariation disease BEFREE The prohibitin T variant does not appear to be associated with risk of ovarian cancer in Australian women. 12821355 2003
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 GeneticVariation disease BEFREE Absence of prohibitin gene mutations in human epithelial ovarian tumors. 8349162 1993