SERPINA4, serpin family A member 4, 5267

N. diseases: 45; N. variants: 3
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.020 GeneticVariation disease BEFREE The SNPs rs2093266 in the SERPINA4 and rs1955656 in the SERPINA5 were associated with the development of severe AKI (KDIGO stage 2-3) in critically ill patients with septic shock. 28270177 2017
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.020 GeneticVariation disease BEFREE Large-scale genotyping reveals two single nucleotide polymorphisms in the BCL2 gene and a single nucleotide polymorphism in the SERPINA4 gene associated with a decreased risk of developing acute kidney injury, supporting the putative role of apoptosis in the pathogenesis of acute kidney injury. 22710204 2012