Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy
0.040 Biomarker phenotype BEFREE Genetic and chemical PIN1 ablation exerted potent antitumor effects through blocking multiple cancer-driving pathways in PDAC. 31148345 2019
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy
0.040 AlteredExpression phenotype BEFREE Pin1 inhibition exerts anticancer activity by blocking multiple cancer-driving pathways in some cancers, but its role in gastric cancer is not fully understood. 31026381 2019
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy
0.040 AlteredExpression phenotype BEFREE We demonstrate that Pin1 is highly overexpressed in human AML and is a promising therapeutic target to block multiple cancer-driving pathways in AML. 29848341 2018
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy
0.040 Biomarker phenotype BEFREE Finally, chemical or genetic Pin1 ablation blocked multiple cancer-driving pathways simultaneously in HCC cells. 28262728 2017