PKNOX1, PBX/knotted 1 homeobox 1, 5316

N. diseases: 34; N. variants: 2
Disease: Teratocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206664
Disease: Teratocarcinoma
Teratocarcinoma 		0.020 Biomarker disease BEFREE By using fibroblasts from DS patients and by overexpressing Prep1 in F9 teratocarcinoma and Prep1(i/i) MEF to single out the role of the protein, we report that excess Prep1 increases the sensitivity of cells to genotoxic stress and the extent of the apoptosis directly correlates with the level of Prep1. 20110257 2010
CUI: C0206664
Disease: Teratocarcinoma
Teratocarcinoma 		0.020 Biomarker disease LHGDN F9 teratocarcinoma cells stably transfected with PREP-1 had an increased DNA binding activity to a PREP-PBX-responsive element. 12871956 2003