PLA2G2A, phospholipase A2 group IIA, 5320

N. diseases: 215; N. variants: 6
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 Biomarker disease BEFREE Using a combination of genetically modified mice, we show that the coordinated action of sPLA2-IIA and 12-LO promotes inflammatory arthritis. 26106157 2015
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 AlteredExpression disease BEFREE Moreover, human synovial fluid, obtained from patients with arthritis and containing sPLA(2) activity, induced EC migration. 11090064 2000
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 Biomarker disease BEFREE Group II PLA2 has been implicated in inflammatory processes in both man and other animals and has been shown to be involved in inflammatory conditions, such as arthritis and sepsis. 8636402 1996