PLA2G2A, phospholipase A2 group IIA, 5320

N. diseases: 215; N. variants: 6
Disease: Endometrioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.320 AlteredExpression disease BEFREE In DIE lesions, CRH, Ucn and CRH-R2 mRNA levels were significantly higher than in OMA (P < 0.01, P < 0.001 and P < 0.05, respectively); DIE lesions showed a higher expression of COX2 (P < 0.01) and PLA2G2A (P < 0.05) mRNA than OMA, which was positively correlated with CRH-R2 mRNA expression (P < 0.05). 27567427 2016
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.320 Biomarker disease BEFREE Using Western blotting, PLA2G2A was detected in all samples of endometriomas, but not in normal endometrium, and immunohistochemistry showed PLA2G2A-specific staining in epithelial cells of endometrioma paraffin sections. 25366587 2015
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.320 Biomarker disease CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850 2015