PLA2G4A, phospholipase A2 group IVA, 5321

N. diseases: 202; N. variants: 15
Disease: Fibrosis, Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.020 Biomarker disease BEFREE Presently, ATX, which produces LPA through its lysophospholipase D activity, has been shown to be a useful laboratory test for the diagnosis and staging of liver fibrosis, whereas PS-PLA<sub>1</sub> and ApoM are considered to be promising clinical markers reflecting the in vivo actions induced by LysoPS and S1P. 30541965 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.020 Biomarker disease BEFREE Lysophospholipase A (LysoPLA), which deacylates lysophospholipids, plays a critical role in mediating the virulence and pathogenesis of parasites and fungi; however, the roles of C. sinensis lysophospholipase A (CsLysoPLA) in C. sinensis-induced liver fibrosis remain unknown. 28623940 2017