PLG, plasminogen, 5340

N. diseases: 586; N. variants: 34
Disease: Eosinophilic esophagitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis 		0.010 AlteredExpression disease BEFREE Profound lost expression of SPINK7 occurs in patients with EoE and is sufficient for unleashing increased proteolytic activity (including urokinase plasminogen activator), impaired barrier function, and production of large quantities of proinflammatory and proallergic cytokines, including thymic stromal lymphopoietin. 29980278 2018