PLXNB1, plexin B1, 5364

N. diseases: 65; N. variants: 0
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.030 Biomarker disease BEFREE Plexin B1 sema domain-containing:Fc fusion proteins suppress RTK signaling and cell growth and inhibit CRPC progression of LNCaP xenografts post-castration <i>in vivo</i> SEMA3C inhibition represents a novel therapeutic strategy for treatment of advanced prostate cancer. 29348142 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.030 Biomarker disease BEFREE The results demonstrated that PLXNB1, but not MMP-9, was the target gene directly related to TMPRSS2-ERG in PCa cell migration and invasion. 28004109 2017
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.030 Biomarker disease BEFREE These results identify a key role for Plexin-B1 and the semaphorin signaling pathway it mediates in prostate cancer. 18024597 2007