PNOC, prepronociceptin, 5368

N. diseases: 103; N. variants: 1
Disease: Mechanical Allodynia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.300 Biomarker phenotype CTD_human Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. 19231294 2009
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.300 Biomarker phenotype CTD_human Nocistatin and prepro-nociceptin/orphanin FQ 160-187 cause nociception through activation of Gi/o in capsaicin-sensitive and of Gs in capsaicin-insensitive nociceptors, respectively. 12665541 2003