PML, promyelocytic leukemia, 5371

N. diseases: 274; N. variants: 14
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 AlteredExpression phenotype BEFREE Promyelocytic leukemia zinc finger (PLZF) is a transcription repressor that was initially isolated as a fusion protein with retinoic acid receptor α. PLZF is aberrantly overexpressed in various human solid tumors, such as clear cell renal carcinoma, glioblastoma, and seminoma. 24821727 2014
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 Biomarker phenotype BEFREE Loss of promyelocytic leukemia protein (PML) nuclear body (NB) formation has been reported in colorectal and other solid tumors. 22155184 2012
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 Biomarker phenotype BEFREE PML loss occurs frequently in hematopoietic and solid tumors. 18566754 2008
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 PosttranslationalModification phenotype BEFREE We therefore assessed the status and expression of the PML gene in solid tumors of multiple histologic origins. 14970276 2004